'
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Lutein (Marigold Petal Extract) (Tagetes erecta) 
20 mg
Zeaxanthin (Marigold Petal Extract) (Tagetes erecta) 
4 mg

Top Medical Research Studies

8
Carotenoids linked to heart health
Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular-Kidney-Metabolic Syndrome Among the General Adult Population.
High relevance to cardiovascular health
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
8
Carotenoids linked to mortality risk
Associations of serum carotenoids with all-cause and cardiovascular mortality in adults with MAFLD.
Moderate relevance to heart health
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.

Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans.
Strongly supports cardiovascular health
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.

We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More

Most Useful Reviews

7.8
Cardiovascular system support
This product positively influences the cardiovascular system, lowering the risk of cardiovascular disease, including atherosclerosis and strokes. Additionally, adequate lutein intake helps prevent retinal detachment and cataracts associated with ageing.
Read More
9
Eye disease prevention
This product optimally balances lutein and zeaxanthin at a 5:1 ratio, as evidenced by the AREDS2 clinical trial. It is effective in preventing conditions such as cataracts and visual disturbances.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
9
Lutein improves mitochondrial function
Targeted Delivery and ROS-Responsive Release of Lutein Nanoassemblies Inhibit Myocardial Ischemia-Reperfusion Injury by Improving Mitochondrial Function.
Highly relevant based on study design
We explored the potential of lutein, a powerful antioxidant, in treating myocardial ischemia-reperfusion injury. To enhance its effectiveness, a novel delivery system named lutein@DTPP was developed, allowing for targeted administration directly to heart tissues.

Our findings showed that this method improved mitochondrial function in heart cells, crucial for reducing damage and preventing cell death. However, while lutein demonstrated benefits in this context, it's important to note that the study primarily focused on a specific injury model, and broader effects on cardiovascular disease might still require more investigation.
Read More
8
Carotenoids linked to heart health
Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular-Kidney-Metabolic Syndrome Among the General Adult Population.
High relevance to cardiovascular health
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
8
Carotenoids linked to mortality risk
Associations of serum carotenoids with all-cause and cardiovascular mortality in adults with MAFLD.
Moderate relevance to heart health
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.

Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans.
Strongly supports cardiovascular health
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.

We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More
8
Carotenoid intake reduces AAC risk
Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014.
Study highly relevant to cardiovascular health
Our analysis focused on how carotenoid intake relates to abdominal aortic calcification (AAC), a crucial indicator of cardiovascular risk. In a study with 2,889 participants, we found that increased consumption of carotenoids—particularly lutein and zeaxanthin—was linked to a reduced risk of severe AAC.

Results showed that higher intakes of various carotenoids, including lutein, significantly lowered the odds of AAC, emphasizing the potential heart health benefits of these nutrients. This suggests that including more carotenoid-rich foods in our diet might be beneficial for our cardiovascular health.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Eye disease prevention
This product optimally balances lutein and zeaxanthin at a 5:1 ratio, as evidenced by the AREDS2 clinical trial. It is effective in preventing conditions such as cataracts and visual disturbances.
7.8
Cardiovascular system support
This product positively influences the cardiovascular system, lowering the risk of cardiovascular disease, including atherosclerosis and strokes. Additionally, adequate lutein intake helps prevent retinal detachment and cataracts associated with ageing.
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